Urine proteomics to discover prognostic biomarkers and improved therapeutic targets for kidney tumors
Discovery of biomarkers for improved precision in oncology remains a critical problem. This is particularly pressing for cancers that currently lack adequate markers for stratification of chemotherapy and targets for…Read More
Is it possible to use cross-linking mass spectrometry to identify protein-protein interactions in living cells?
Cross-linking mass spectrometry is a powerful tool to elucidate protein-protein interactions and macromolecular structure based on cross-linker distances between specific amino acid residues. In a recent study led by Zheng…Read More
UltraQuant: Open framework for running MaxQuant mass spectrometry proteomics algorithms on Linux computer clusters
While computational genomics methods have been greatly advanced by open development in distributed computing environments, computational tools for mass spectrometry proteomics remain tethered to proprietary and often outdated operating systems.…Read More