Interact

Jul 20, 2017

Rational combination therapy for acute myeloid leukemia

Functional genomics technology has brought numerous advances to cancer biology and to the discovery of new therapeutic targets. Now, collaborative research that was carried out with many colleagues across the country…

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  • Alex Kentsis

Mar 12, 2017

Human PGBD5 DNA transposase promotes site-specific oncogenic mutations in solid tumors

While some human cancers occur as a result of age-dependent accumulation of genetic mutations, and others are caused by deficiencies in DNA replication or repair, the causes of many oncogenic…

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Dec 31, 2015

ProteoModlR for quantitative proteomics pathway modeling

To enable quantitative analysis of post-translational protein modifications, Paolo Cifani and Mojdeh Shakiba in the lab developed ProteoModlR, a R program for quantitative analysis of relative and absolute abundance and…

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Nov 02, 2015

Next-Gen Methods in Pharmacology

Welcome to the course page for Next-Gen Methods in Pharmacology! Graduate Program in Pharmacology, Weill Cornell Medical College and Sloan Kettering Institute Course Directors: Michael Kharas & Alex Kentsis This…

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Sep 27, 2015

Human PGBD5 induces DNA transposition

Transposons are mobile genetic elements that are found in most living organisms. We have now found that human PGBD5 can induce DNA transposition in human cells. The apparent conservation of…

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