Cross-linking mass spectrometry is a powerful tool to elucidate protein-protein interactions and macromolecular structure based on cross-linker distances between specific amino acid residues. In a recent study led by Zheng…
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While computational genomics methods have been greatly advanced by open development in distributed computing environments, computational tools for mass spectrometry proteomics remain tethered to proprietary and often outdated operating systems.…
Read MoreA few years ago, we published a paper reporting PGBD5 as an oncogenic mutator in human cancer. This included measuring its expression in human tissues and mapping its association with…
Read MoreGenetically engineered mouse models of human cancers have proven to be essential for the elucidation of basic molecular mechanisms of cancer pathogenesis and their therapeutic targeting. However, for many genetic…
Read MoreDysregulated control of gene expression is probably one of the essential features of almost every cancer. The causes of this phenomenon vary, but emerging research is converging on the idea…
Read MoreThink PDL1 activity is a function of tumor burden? Maybe not in some unique INI1 negative pediatric tumors. New study out by Suzanne Forrest and @janeway_MD from @DFBC_PedCare in @CCR_AACR. Can't wait to see what the trial shows. Stay tuned! https://t.co/O4YSdIvcmg
You’ve met histone serotonylation now meet dopaminylation and it’s role in drug related plasticity! @ScienceMagazine #epigenetics Thanks to all our amazing collaborators for their expertise in bringing this together 💪🏻 https://t.co/YuWKie4ERh
AIM2 is highly expressed in neurons, new paper examines its function in brain development, very provocative! https://t.co/SLHuweIvG8
