While some human cancers occur as a result of age-dependent accumulation of genetic mutations, and others are caused by deficiencies in DNA replication or repair, the causes of many oncogenic…
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To enable quantitative analysis of post-translational protein modifications, Paolo Cifani and Mojdeh Shakiba in the lab developed ProteoModlR, a R program for quantitative analysis of relative and absolute abundance and…
Read MoreWelcome to the course page for Next-Gen Methods in Pharmacology! Graduate Program in Pharmacology, Weill Cornell Medical College and Sloan Kettering Institute Course Directors: Michael Kharas & Alex Kentsis This…
Read MoreTransposons are mobile genetic elements that are found in most living organisms. We have now found that human PGBD5 can induce DNA transposition in human cells. The apparent conservation of…
Read MoreRecent developments in quantitative high-resolution mass spectrometry have led to significant improvements in the sensitivity and specificity of biochemical analyses of cellular reactions, protein-protein interactions, and small molecule drug discovery.…
Read MoreFirst experimental demonstration of protein identification with *single-molecule sensitivity*. A huge breakthrough from the labs of Edward Marcotte and Eric Anslyn @EricAnslyn https://t.co/U2wr1kD4W3
This man. @rosslevinemd
"I dedicate my miles to the patients at @sloan_kettering." Read Dr. Ross Levine's story: https://t.co/bQgOLcTyOw
Today, SCoPE-MS appeared in @GenomeBiology at https://t.co/cAKLET86Wd
Thanks to @biorxivpreprint, the preprint (https://t.co/Ed28dJ8gJO) was:
-- Reproduced by several labs
-- Accessed > 40,000 times
-- Cited > 20 times
Thanks to the colleagues & reviewers who helped improve it!
We already knew all invasive epithelial ovarian pts should be tested for BRCA1/2. This makes it imperative that it be done at diagnosis.
Maintenance Olaparib in Patients with Newly Diagnosed Advanced Ovarian Cancer | NEJM https://t.co/5yJ98ukTL0
