A few years ago, we published a paper reporting PGBD5 as an oncogenic mutator in human cancer. This included measuring its expression in human tissues and mapping its association with…
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Genetically engineered mouse models of human cancers have proven to be essential for the elucidation of basic molecular mechanisms of cancer pathogenesis and their therapeutic targeting. However, for many genetic…
Read MoreDysregulated control of gene expression is probably one of the essential features of almost every cancer. The causes of this phenomenon vary, but emerging research is converging on the idea…
Read MoreAs we and others have described recently, modern mass spectrometry permits quantitative and sensitive measurements of both protein abundance and their chemical modifications, as proxies of biological and pathological activities.…
Read MoreFunctional genomics technology has brought numerous advances to cancer biology and to the discovery of new therapeutic targets. Now, collaborative research that was carried out with many colleagues across the country…
Read MoreReview Commons is now LIVE. @PLOS We are excited to be part of this experiment in journal-independent peer review led by @ASAPbio_ and @embojournal with 17 journals in total. https://t.co/1xx7p2GGyN
What a thread! what great comments! Awesome awesomeness thanks! https://t.co/wxYRRUH99U
That's equivalent to more than one million biomedical NIH research grants, or enough to fund the current national program for more than 200 years! What Did the U.S. Get for $2 Trillion in Afghanistan? https://t.co/gkGF6jBprf
Could evolution of cellular nuclei be promoted by inter-organismal conflict? Escape from CRISPR interference by phages in bacteria suggests that this may be so: https://t.co/putckkIRw6
Important work @Armstrong_dfci and colleagues on the new Menin-MLL Inhibitor for AML. Clinical trial is highly promising and imminent. https://t.co/vtuyS07TXd
