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May 29, 2015

Fabrication of Capillary Columns with Integrated Frits for Mass Spectrometry

Miniaturization of columns for liquid chromatography has greatly enhanced its sensitivity and resolution. Here, we provide a detailed protocol that describes the fabrication of fused silica capillaries with frits and their packing with…

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May 29, 2015

Fabrication of Nanoelectrospray Emitters for LC-MS

Ionization efficiency and consequently the sensitivity of mass spectrometric analyses strongly depend on the geometry of nanoelectrospray emitter used, particularly on the terminal inner diameter (ID) of the tip. Here,…

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Oct 02, 2014

Blocking disulfide-bridged oncogenic receptor signalling in leukemia using N-acetylcysteine

A subset of human acute lymphoblastic leukemias are driven by mutations of the interleukin-7 receptor (IL7R) and cytokine receptor-like factor 2 (CRLF2), causing aberrant signaling due to disulfide-mediated receptor activation.…

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Jun 05, 2014

Paolo Cifani is selected as American-Italian Cancer Foundation Fellow

Congratulations to Paolo for being selected as American-Italian Cancer Foundation Fellow!  For more than 30 years, AICF has supported both improved patient care and innovative cancer research, and we are grateful for…

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Jan 26, 2014

Lecture: Mechanisms of cancer drug susceptibility and resistance

Mechanisms of cancer drug susceptibility and resistance, lecture for the SKI/Cornell Pharmacology Graduate Program, May 2014: pdf

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