While some human cancers occur as a result of age-dependent accumulation of genetic mutations, and others are caused by deficiencies in DNA replication or repair, the causes of many oncogenic…
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To enable quantitative analysis of post-translational protein modifications, Paolo Cifani and Mojdeh Shakiba in the lab developed ProteoModlR, a R program for quantitative analysis of relative and absolute abundance and…
Read MoreWelcome to the course page for Next-Gen Methods in Pharmacology! Graduate Program in Pharmacology, Weill Cornell Medical College and Sloan Kettering Institute Course Directors: Michael Kharas & Alex Kentsis This…
Read MoreTransposons are mobile genetic elements that are found in most living organisms. We have now found that human PGBD5 can induce DNA transposition in human cells. The apparent conservation of…
Read MoreRecent developments in quantitative high-resolution mass spectrometry have led to significant improvements in the sensitivity and specificity of biochemical analyses of cellular reactions, protein-protein interactions, and small molecule drug discovery.…
Read MoreCourts are clogged with millions of debt collection cases. Nearly half are for unpaid medical costs. And although America is not supposed to have debtors prisons, in places like Coffeyville KS, people are getting sent to jail. @propublica https://t.co/iBIvio7zCv
Contribution of retrotransposition to developmental disorders https://t.co/mfdgKjizou #transposon
Read new work from Frederic Kaye and colleagues on new models and therapies for #adenoidcysticcarcinoma including our MYBMIM inhibitor: MYB-activated models for testing therapeutic agents in adenoid cystic carcinoma: https://t.co/gJYPHHbcfW @amyhellerdesign @accrf_org
Latest review from E.Koonin and co.🔥Many interesting thinks about arms race of mobile genetic elements and host defense system. No borders. Evolutionary entanglement of mobile genetic elements and host defence systems: guns for hire @NatureRevGenet https://t.co/jG31bhxFqi
