As we and others have described recently, modern mass spectrometry permits quantitative and sensitive measurements of both protein abundance and their chemical modifications, as proxies of biological and pathological activities.…
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Functional genomics technology has brought numerous advances to cancer biology and to the discovery of new therapeutic targets. Now, collaborative research that was carried out with many colleagues across the country…
Read MoreWhile some human cancers occur as a result of age-dependent accumulation of genetic mutations, and others are caused by deficiencies in DNA replication or repair, the causes of many oncogenic…
Read MoreTo enable quantitative analysis of post-translational protein modifications, Paolo Cifani and Mojdeh Shakiba in the lab developed ProteoModlR, a R program for quantitative analysis of relative and absolute abundance and…
Read MoreWelcome to the course page for Next-Gen Methods in Pharmacology! Graduate Program in Pharmacology, Weill Cornell Medical College and Sloan Kettering Institute Course Directors: Michael Kharas & Alex Kentsis This…
Read MoreThink PDL1 activity is a function of tumor burden? Maybe not in some unique INI1 negative pediatric tumors. New study out by Suzanne Forrest and @janeway_MD from @DFBC_PedCare in @CCR_AACR. Can't wait to see what the trial shows. Stay tuned! https://t.co/O4YSdIvcmg
You’ve met histone serotonylation now meet dopaminylation and it’s role in drug related plasticity! @ScienceMagazine #epigenetics Thanks to all our amazing collaborators for their expertise in bringing this together 💪🏻 https://t.co/YuWKie4ERh
AIM2 is highly expressed in neurons, new paper examines its function in brain development, very provocative! https://t.co/SLHuweIvG8
