Transposons are mobile genetic elements that are found in most living organisms. We have now found that human PGBD5 can induce DNA transposition in human cells. The apparent conservation of…
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Recent developments in quantitative high-resolution mass spectrometry have led to significant improvements in the sensitivity and specificity of biochemical analyses of cellular reactions, protein-protein interactions, and small molecule drug discovery.…
Read MoreThis protocol describes a modified version of flanking sequence exponential anchored (FLEA) PCR. The original FLEA-PCR method was developed to amplify integration sites of retroviruses or retro-transposons. Such transposons contain…
Read More[caption id="attachment_287" align="alignnone" width="720"] Conor O'Donnell (UC Dublin), Mondira Ray (Pitt), Camila Villasante (Johns Hopkins), Huong Tang (UMass).[/caption]
Read MoreWe are thrilled to welcome Lauren Forbes as a PhD thesis student. Lauren is a graduate student in Pharmacology, with an interest in drug design and cancer therapeutics. She obtained…
Read MoreSo excited to share our publication today! Working with the awesome @markwbudde, A. Granados, and other brilliant minds in the @ElowitzLab, Lois Lab, and @LongCai_Lab, we developed a synthetic recording system to image single cell lineage history. https://science.sciencemag.org/content/372/6538/eabb3099
Excited to share our latest work published today: Silencing of LINE-1 Retrotransposons is a Selective Dependency of Myeloid Leukemia
https://www.nature.com/articles/s41588-021-00829-8
@CRI_UTSW @UTSWNews @NatureGenet
Delighted that our new paper on the role of extrachromosomal DNA elements as mobile enhancers is online. Wonderful collaboration with the lab of Chia-Lin Wei. https://www.cell.com/cancer-cell/fulltext/S1535-6108(21)00164-1
Dr. Scott Keeney (@Spo11Rulz) has been studying a protein called Spo11 for two decades. But it wasn't until a postdoc in Dr. Keeney's lab, @ccb_Lab, came along that they were able to answer key questions about Spo11's role in #meiosis. https://bit.ly/3t3VNNY
Sharing this piece about my friend and colleague Buzz Baldwin who passed away last month. https://med.stanford.edu/news/all-news/2021/03/Robert-Baldwin-biochemistry-department-dies-at-93.html Buzz was a pioneer in biochemistry and a wonderful, caring person. We are all missing him @StanfordBiochem.
