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Lysine mimicking small molecules get ubiquitylated, monovalent degraders. Awesome! @J_A_C_S
The Matters Arising discussion about phosphosite effects on protein thermal stability as a proxy for functional importance in this month's issue of @naturemethods feels like a cool example of how scientific exchange should happen.
Happy to share our latest story. Huge thanks to all authors @trompoukilab @ClapsTom @KaterinaPolizou @s_lefkopoulos @AsifaAkhtar1 @Nina_CabezasW @dominic_grun @rita_rebollo https://www.nature.com/articles/s41556-021-00707-9
My 1st first author paper was published today! We used Azo and the timsTOF Pro to develop a fast and reproducible bottom-up method to characterize the heart proteome from small amounts of tissue. Check it out! https://pubs.acs.org/doi/10.1021/acs.jproteome.1c00446
Dr. David Scheinberg's team (@DASLab_MSKCC) at @sloan_kettering and @EinsteinMed utilized the IgG protease “IdeS” to reprogram CAR T cells to defeat humoral #immune attacks ⚔️.