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Alex Kentsis
- Nov 05, 2020
KRG Outreach: Biology and Pharmacology of Childhood and Developmental Cancers
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Load More...Fanstastic! Needs confirmation and further studies, but makes chemical sense: A lysine–cysteine redox switch with an NOS bridge regulates enzyme function.
https://www.nature.com/articles/s41586-021-03513-3We're thrilled to share our latest review on molecular glue degraders! Compounds bring proteins together with surprising ease - we discuss how understanding drug-induced interfaces can help in monovalent degrader development 👉 https://bit.ly/2QFk7Id @CellChemBiol @zkozicka
