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A few favorite publications:
A transposase-derived gene required for human brain development
Overcoming clinical resistance to EZH2 inhibition using rational epigenetic combination therapy
Epigenetic mechanisms controlling human leukemia stem cells and therapy resistance
Childhood cancer mutagenesis caused by a domesticated DNA transposase
J Proteome Research 2022
Quantitative Cell Proteomic Atlas: Pathway-Scale Targeted Mass Spectrometry for High-Resolution Functional Profiling of Cell Signaling
J Proteome Research 2021
Discovery of protein modifications using differential tandem mass spectrometry proteomics
Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia
Pediatric Blood & Cancer 2020
Why do young people get cancer?
Frontiers in Pediatrics 2020
Developmental mutators and early onset cancer
JCI Insight 2019
Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms’ tumor
J Proteome Research 2019
Optimized cross-linking mass spectrometry for in situ interaction proteomics
J Proteome Research 2018
ProteomeGenerator: A framework for comprehensive proteomics based on de novo transcriptome assembly and high-accuracy peptide mass spectral matching
Cancer Discovery 2018
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia
Nature Communications 2018
Peptidomimetic blockade of MYB in acute myeloid leukemia
Science Translational Medicine 2017
Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors
Molecular & Cellular Proteomics 2017
High sensitivity quantitative proteomics using automated multidimensional nano-flow chromatography and accumulated ion monitoring on quadrupole-Orbitrap-linear ion trap mass spectrometer
Nature Genetics 2017
PGBD5 promotes site-specific oncogenic mutations in human tumors
BMC Genomics 2016.
Forward genetic screen of human transposase genomic rearrangements
Genomic DNA transposition induced by human PGBD5.
Pediatr Blood Cancer 2016.
Integrating genomics into clinical pediatric oncology using the molecular tumor board at MSKCC.
J Proteome Res 2015.
A high-efficiency cellular extraction system for biological proteomics.
British Journal of Haemotology 2014.
Targeting oncogenic interleukin-7 receptor signalling with N-acetylcysteine in T cell acute lymphoblastic leukaemia.
EMBO Molecular Medicine 2013.
Urine proteomics for discovery of improved diagnostic markers of Kawasaki disease.
Nature Medicine 2012.
Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia.
Ann Emerg Med 2010.
Discovery and validation of urine markers of acute appendicitis using high accuracy mass spectrometry.
Proteomics Clin Appl 2009.
Urine proteomics for profiling of human disease using high accuracy mass spectrometry.
Ribavirin suppresses eIF4E- mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap.
Unfolded state of polyalanine is a segmented polyproline II helix.
Control of biochemical reactions through supramolecular RING domain self-assembly..
Nature Struct Biol 2000.
D/H amide kinetic isotope effects reveal when hydrogen bonds form during protein folding.
Kentsis Research Group
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