Cross-linking mass spectrometry is a powerful tool to elucidate protein-protein interactions and macromolecular structure based on cross-linker distances between specific amino acid residues. In a recent study led by Zheng…
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Dysregulated control of gene expression is probably one of the essential features of almost every cancer. The causes of this phenomenon vary, but emerging research is converging on the idea…
Read MoreTransposons are mobile genetic elements that are found in most living organisms. We have now found that human PGBD5 can induce DNA transposition in human cells. The apparent conservation of…
Read MoreA subset of human acute lymphoblastic leukemias are driven by mutations of the interleukin-7 receptor (IL7R) and cytokine receptor-like factor 2 (CRLF2), causing aberrant signaling due to disulfide-mediated receptor activation.…
Read MoreNCAB asks for help from administration as NCI deals with deluge of grant applications https://t.co/STEp0uD60h Great that there is so much new science, sad that grants with 11% scores won't be funded @ChrisVakoc
