Targeting oncogenic transcription factors
Dysregulated control of gene expression is probably one of the essential features of almost every cancer. The causes of this phenomenon vary, but emerging research is converging on the idea…
Read MoreCategory archives for Paper
Human PGBD5 induces DNA transposition
Transposons are mobile genetic elements that are found in most living organisms. We have now found that human PGBD5 can induce DNA transposition in human cells. The apparent conservation of…
Read More-
Alex Kentsis
Blocking disulfide-bridged oncogenic receptor signalling in leukemia using N-acetylcysteine
A subset of human acute lymphoblastic leukemias are driven by mutations of the interleukin-7 receptor (IL7R) and cytokine receptor-like factor 2 (CRLF2), causing aberrant signaling due to disulfide-mediated receptor activation.…
Read More-
Alex Kentsis
Twitter Feed
Load More...This man. @rosslevinemd
"I dedicate my miles to the patients at @sloan_kettering." Read Dr. Ross Levine's story: https://t.co/bQgOLcTyOw
Today, SCoPE-MS appeared in @GenomeBiology at https://t.co/cAKLET86Wd
Thanks to @biorxivpreprint, the preprint (https://t.co/Ed28dJ8gJO) was:
-- Reproduced by several labs
-- Accessed > 40,000 times
-- Cited > 20 times
Thanks to the colleagues & reviewers who helped improve it!We already knew all invasive epithelial ovarian pts should be tested for BRCA1/2. This makes it imperative that it be done at diagnosis.
Maintenance Olaparib in Patients with Newly Diagnosed Advanced Ovarian Cancer | NEJM https://t.co/5yJ98ukTL0
1
