Discovery of biomarkers for improved precision in oncology remains a critical problem. This is particularly pressing for cancers that currently lack adequate markers for stratification of chemotherapy and targets for…
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Cross-linking mass spectrometry is a powerful tool to elucidate protein-protein interactions and macromolecular structure based on cross-linker distances between specific amino acid residues. In a recent study led by Zheng…
Read MoreDysregulated control of gene expression is probably one of the essential features of almost every cancer. The causes of this phenomenon vary, but emerging research is converging on the idea…
Read MoreTransposons are mobile genetic elements that are found in most living organisms. We have now found that human PGBD5 can induce DNA transposition in human cells. The apparent conservation of…
Read MoreA subset of human acute lymphoblastic leukemias are driven by mutations of the interleukin-7 receptor (IL7R) and cytokine receptor-like factor 2 (CRLF2), causing aberrant signaling due to disulfide-mediated receptor activation.…
Read MoreWhat is this strange, giant tube attached to a hand supposed to be?
#Metabolomics revealed a weakness in relapsing acute lymphoblastic leukemia, which occurs in children. Targeting specific enzymes near this weakness may provide a route to improved outcomes. #illuminatingresearch. Read more: https://t.co/9AIguEMKOE
Review Commons is now LIVE. @PLOS We are excited to be part of this experiment in journal-independent peer review led by @ASAPbio_ and @embojournal with 17 journals in total. https://t.co/1xx7p2GGyN
What a thread! what great comments! Awesome awesomeness thanks! https://t.co/wxYRRUH99U
