A few years ago, we published a paper reporting PGBD5 as an oncogenic mutator in human cancer. This included measuring its expression in human tissues and mapping its association with…
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Genetically engineered mouse models of human cancers have proven to be essential for the elucidation of basic molecular mechanisms of cancer pathogenesis and their therapeutic targeting. However, for many genetic…
Read MoreRecent developments in quantitative high-resolution mass spectrometry have led to significant improvements in the sensitivity and specificity of biochemical analyses of cellular reactions, protein-protein interactions, and small molecule drug discovery.…
Read MoreThis protocol describes a modified version of flanking sequence exponential anchored (FLEA) PCR. The original FLEA-PCR method was developed to amplify integration sites of retroviruses or retro-transposons. Such transposons contain…
Read MoreMiniaturization of columns for liquid chromatography has greatly enhanced its sensitivity and resolution. Here, we provide a detailed protocol that describes the fabrication of fused silica capillaries with frits and their packing with…
Read MoreThis man. @rosslevinemd
"I dedicate my miles to the patients at @sloan_kettering." Read Dr. Ross Levine's story: https://t.co/bQgOLcTyOw
Today, SCoPE-MS appeared in @GenomeBiology at https://t.co/cAKLET86Wd
Thanks to @biorxivpreprint, the preprint (https://t.co/Ed28dJ8gJO) was:
-- Reproduced by several labs
-- Accessed > 40,000 times
-- Cited > 20 times
Thanks to the colleagues & reviewers who helped improve it!
We already knew all invasive epithelial ovarian pts should be tested for BRCA1/2. This makes it imperative that it be done at diagnosis.
Maintenance Olaparib in Patients with Newly Diagnosed Advanced Ovarian Cancer | NEJM https://t.co/5yJ98ukTL0
