While computational genomics methods have been greatly advanced by open development in distributed computing environments, computational tools for mass spectrometry proteomics remain tethered to proprietary and often outdated operating systems.…
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A few years ago, we published a paper reporting PGBD5 as an oncogenic mutator in human cancer. This included measuring its expression in human tissues and mapping its association with…
Read MoreGenetically engineered mouse models of human cancers have proven to be essential for the elucidation of basic molecular mechanisms of cancer pathogenesis and their therapeutic targeting. However, for many genetic…
Read MoreRecent developments in quantitative high-resolution mass spectrometry have led to significant improvements in the sensitivity and specificity of biochemical analyses of cellular reactions, protein-protein interactions, and small molecule drug discovery.…
Read MoreThis protocol describes a modified version of flanking sequence exponential anchored (FLEA) PCR. The original FLEA-PCR method was developed to amplify integration sites of retroviruses or retro-transposons. Such transposons contain…
Read MoreOutstanding talk by Dr. Alex Kentsis @KentsisResearch describing his work using novel genomic and proteomic approaches for cancer therapy, including #leukemia #leusm @sloan_kettering @WeillCornell
2Improved protein structure prediction using potentials from deep learning https://t.co/o7KdQywMn1
@JaroszLab : A Non-amyloid Prion Particle that Activates a Heritable Gene Expression Program https://t.co/JwLBU3TaDA
Engraftment of rare, pathogenic donor hematopoietic mutations in unrelated hematopoietic stem cell transplantation https://t.co/A8lyzHSshY
