A few years ago, we published a paper reporting PGBD5 as an oncogenic mutator in human cancer. This included measuring its expression in human tissues and mapping its association with…
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Genetically engineered mouse models of human cancers have proven to be essential for the elucidation of basic molecular mechanisms of cancer pathogenesis and their therapeutic targeting. However, for many genetic…
Read MoreRecent developments in quantitative high-resolution mass spectrometry have led to significant improvements in the sensitivity and specificity of biochemical analyses of cellular reactions, protein-protein interactions, and small molecule drug discovery.…
Read MoreThis protocol describes a modified version of flanking sequence exponential anchored (FLEA) PCR. The original FLEA-PCR method was developed to amplify integration sites of retroviruses or retro-transposons. Such transposons contain…
Read MoreMiniaturization of columns for liquid chromatography has greatly enhanced its sensitivity and resolution. Here, we provide a detailed protocol that describes the fabrication of fused silica capillaries with frits and their packing with…
Read MoreExtensive horizontal gene transfer in human microbiota. Real-time capture of horizontal gene transfers from gut microbiota by engineered CRISPR-Cas acquisition. https://t.co/K7r3Cb9aCE
Countless examples of this, but requires just right pairing between students and post-doctoral fellows. Undergraduate students can be a boon to your lab. https://t.co/PlehMF97vH
My lab’s new paper describing mutations and copy-number alterations associated with cancer prognosis has been published. We also introduce a web resource – https://t.co/20fFzSgSEu – that will be useful for the cancer research community. https://t.co/nqmm2rGkd2
Whoa! Structure of a cytochrome-based bacterial nanowire. https://t.co/eOPgw37mzf
