While computational genomics methods have been greatly advanced by open development in distributed computing environments, computational tools for mass spectrometry proteomics remain tethered to proprietary and often outdated operating systems.…
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A few years ago, we published a paper reporting PGBD5 as an oncogenic mutator in human cancer. This included measuring its expression in human tissues and mapping its association with…
Read MoreGenetically engineered mouse models of human cancers have proven to be essential for the elucidation of basic molecular mechanisms of cancer pathogenesis and their therapeutic targeting. However, for many genetic…
Read MoreRecent developments in quantitative high-resolution mass spectrometry have led to significant improvements in the sensitivity and specificity of biochemical analyses of cellular reactions, protein-protein interactions, and small molecule drug discovery.…
Read MoreThis protocol describes a modified version of flanking sequence exponential anchored (FLEA) PCR. The original FLEA-PCR method was developed to amplify integration sites of retroviruses or retro-transposons. Such transposons contain…
Read MoreWhat is this strange, giant tube attached to a hand supposed to be?
#Metabolomics revealed a weakness in relapsing acute lymphoblastic leukemia, which occurs in children. Targeting specific enzymes near this weakness may provide a route to improved outcomes. #illuminatingresearch. Read more: https://t.co/9AIguEMKOE
Review Commons is now LIVE. @PLOS We are excited to be part of this experiment in journal-independent peer review led by @ASAPbio_ and @embojournal with 17 journals in total. https://t.co/1xx7p2GGyN
What a thread! what great comments! Awesome awesomeness thanks! https://t.co/wxYRRUH99U
