While computational genomics methods have been greatly advanced by open development in distributed computing environments, computational tools for mass spectrometry proteomics remain tethered to proprietary and often outdated operating systems.…
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A few years ago, we published a paper reporting PGBD5 as an oncogenic mutator in human cancer. This included measuring its expression in human tissues and mapping its association with…
Read MoreGenetically engineered mouse models of human cancers have proven to be essential for the elucidation of basic molecular mechanisms of cancer pathogenesis and their therapeutic targeting. However, for many genetic…
Read MoreRecent developments in quantitative high-resolution mass spectrometry have led to significant improvements in the sensitivity and specificity of biochemical analyses of cellular reactions, protein-protein interactions, and small molecule drug discovery.…
Read MoreThis protocol describes a modified version of flanking sequence exponential anchored (FLEA) PCR. The original FLEA-PCR method was developed to amplify integration sites of retroviruses or retro-transposons. Such transposons contain…
Read MoreCourts are clogged with millions of debt collection cases. Nearly half are for unpaid medical costs. And although America is not supposed to have debtors prisons, in places like Coffeyville KS, people are getting sent to jail. @propublica https://t.co/iBIvio7zCv
Contribution of retrotransposition to developmental disorders https://t.co/mfdgKjizou #transposon
Read new work from Frederic Kaye and colleagues on new models and therapies for #adenoidcysticcarcinoma including our MYBMIM inhibitor: MYB-activated models for testing therapeutic agents in adenoid cystic carcinoma: https://t.co/gJYPHHbcfW @amyhellerdesign @accrf_org
Latest review from E.Koonin and co.🔥Many interesting thinks about arms race of mobile genetic elements and host defense system. No borders. Evolutionary entanglement of mobile genetic elements and host defence systems: guns for hire @NatureRevGenet https://t.co/jG31bhxFqi
