- Jul 20, 2022
We are very excited to have Anna Antonova join us as a graduate student for her PhD thesis research to define mechanisms of ALT signaling and its peptidomimetic inhibitors for cancer therapy.
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Look forward to this wonderful meeting https://meetings.cshl.edu/meetings.aspx?meet=transpose&year=22 to present normal functions of PGBD5 in brain development, its disease activity as developmental mutator in medulloblastomas https://www.biorxiv.org/content/10.1101/2022.07.05.498128v1, and dispel the controversy about its DNA transposase activity.
Fascinating work from @MattWilsonLab with Alison Hickmand and Fred Dyda and colleagues! Transposase N-terminal phosphorylation and asymmetric transposon ends inhibit piggyBac transposition in mammalian cells https://www.biorxiv.org/content/10.1101/2022.09.26.509586v1
Pretty cool open-source fraction collector/spotter for LC-MALDI proteomics from Jarrod Marto, Scott Ficarro et al: https://pubmed.ncbi.nlm.nih.gov/35518277/
Transposon friends, in preparation for the CSHL Transposable Element Meeting, I want you to answer this question: What is human PiggyBac Transposable Element Derived 5 (PGBD5)?
I’m very proud to share the first paper from my lab @TheCrick, a wonderful collaboration with @jrengen. Made possible by Aleksandra Pajak and @tmonsterphd, with contributions from @funtoshs and @BetkaRoe. A summary🧵: 1/11 https://www.biorxiv.org/content/10.1101/2022.09.23.509153v1