Publications

Papers

All publications in:

A few favorite publications:

J Proteome Research 2024

Proteomic Barcoding Platform for Macromolecular Screening and Delivery

Cold Spring Harb Perspect Med 2024

Toward a Unified Theory of Why Young People Develop Cancer

bioRxiv 2023

A transposase-derived gene required for human brain development

Cancer Discovery 2024

Overcoming clinical resistance to EZH2 inhibition using rational epigenetic combination therapy

bioRxiv 2022

Epigenetic mechanisms controlling human leukemia stem cells and therapy resistance

PGBD5 mutator Science Advances 2024

Childhood cancer mutagenesis caused by transposase-derived PGBD5

J Proteome Research 2022

Quantitative Cell Proteomic Atlas: Pathway-Scale Targeted Mass Spectrometry for High-Resolution Functional Profiling of Cell Signaling

J Proteome Research 2021

Discovery of protein modifications using differential tandem mass spectrometry proteomics

eLife 2021

Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia

Pediatric Blood & Cancer 2020

Why do young people get cancer?

Frontiers in Pediatrics 2020

Developmental mutators and early onset cancer

JCI Insight 2019

Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms’ tumor

J Proteome Research 2019

Optimized cross-linking mass spectrometry for in situ interaction proteomics

J Proteome Research 2018

ProteomeGenerator: A framework for comprehensive proteomics based on de novo transcriptome assembly and high-accuracy peptide mass spectral matching

Cancer Discovery 2018

MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia

Nature Communications 2018

Peptidomimetic blockade of MYB in acute myeloid leukemia

Science Translational Medicine 2017

Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors

Molecular & Cellular Proteomics 2017

High sensitivity quantitative proteomics using automated multidimensional nano-flow chromatography and accumulated ion monitoring on quadrupole-Orbitrap-linear ion trap mass spectrometer

Nature Genetics 2017

PGBD5 promotes site-specific oncogenic mutations in human tumors

BMC Genomics 2016.

Forward genetic screen of human transposase genomic rearrangements

eLife 2015.

Genomic DNA transposition induced by human PGBD5.

Pediatr Blood Cancer 2016.

Integrating genomics into clinical pediatric oncology using the molecular tumor board at MSKCC.

J Proteome Res 2015.

A high-efficiency cellular extraction system for biological proteomics.

British Journal of Haemotology 2014.

Targeting oncogenic interleukin-7 receptor signalling with N-acetylcysteine in T cell acute lymphoblastic leukaemia.

EMBO Molecular Medicine 2013.

Urine proteomics for discovery of improved diagnostic markers of Kawasaki disease.

Nature Medicine 2012.

Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia.

Ann Emerg Med 2010.

Discovery and validation of urine markers of acute appendicitis using high accuracy mass spectrometry.

Proteomics Clin Appl 2009.

Urine proteomics for profiling of human disease using high accuracy mass spectrometry.

PNAS 2004.

Ribavirin suppresses eIF4E- mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap.

Proteins 2004.

Unfolded state of polyalanine is a segmented polyproline II helix.

PNAS 2002.

Control of biochemical reactions through supramolecular RING domain self-assembly..

Nature Struct Biol 2000.

D/H amide kinetic isotope effects reveal when hydrogen bonds form during protein folding.