To enable quantitative analysis of post-translational protein modifications, Paolo Cifani and Mojdeh Shakiba in the lab developed ProteoModlR, a R program for quantitative analysis of relative and absolute abundance and…
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Welcome to the course page for Next-Gen Methods in Pharmacology! Graduate Program in Pharmacology, Weill Cornell Medical College and Sloan Kettering Institute Course Directors: Michael Kharas & Alex Kentsis This…
Read MoreTransposons are mobile genetic elements that are found in most living organisms. We have now found that human PGBD5 can induce DNA transposition in human cells. The apparent conservation of…
Read MoreRecent developments in quantitative high-resolution mass spectrometry have led to significant improvements in the sensitivity and specificity of biochemical analyses of cellular reactions, protein-protein interactions, and small molecule drug discovery.…
Read MoreThis protocol describes a modified version of flanking sequence exponential anchored (FLEA) PCR. The original FLEA-PCR method was developed to amplify integration sites of retroviruses or retro-transposons. Such transposons contain…
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