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Category archives for Paper

Jan 22, 2021

A new year for new science and a new science publishing model: Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia

Past year has certainly been anything but ordinary. While managing the pandemic, we also continued research on how diverse forms of acute myeloid leukemias, caused by different oncogenes, may co-opt…

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May 18, 2020

Why do young people get cancer? Developmental mutators, mutagens, and inheritance.

Much of human cancer is a product of aging, from errors during DNA replication, environmental exposures, and the inevitable failure of our bodies. What causes cancer in young people and…

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Aug 06, 2019

Urine proteomics to discover prognostic biomarkers and improved therapeutic targets for kidney tumors

Discovery of biomarkers for improved precision in oncology remains a critical problem. This is particularly pressing for cancers that currently lack adequate markers for stratification of chemotherapy and targets for…

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Jun 05, 2019

Is it possible to use cross-linking mass spectrometry to identify protein-protein interactions in living cells?

Cross-linking mass spectrometry is a powerful tool to elucidate protein-protein interactions and macromolecular structure based on cross-linker distances between specific amino acid residues. In a recent study led by Zheng…

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Jan 09, 2018

Targeting oncogenic transcription factors

Dysregulated control of gene expression is probably one of the essential features of almost every cancer. The causes of this phenomenon vary, but emerging research is converging on the idea…

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